Connexin Gene Expression in Seminiferous Tubules of the Sprague-Dawley Rat1
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چکیده
منابع مشابه
Maturational changes in connexin 43 expression in the seminiferous tubules may depend on thyroid hormone action
INTRODUCTION Connexin 43 (Cx43) mediates the effect of thyroid hormone on Sertoli cell maturation in vitro. We investigated the influence of triiodothyronine (T3) administration on Cx43 expression in relation to the progress in seminiferous tubule maturation. MATERIAL AND METHODS Male rats were daily injected with 100 µg T3/kg body weight from birth until postnatal day (pnd) 5 (transient trea...
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Female Sprague-Dawley rats were exposed to a single, graded dose of either of two highly effective mammary chemical carcin ogens, 7,12-dimethylbenzanthracene (DMBA) or A/-methylnitrosourea, in order to determine the number of mammary cancers per rat induced by a range of carcinogenic doses. These data were then used to separately construct dose-response curves characteristic for DMBAand A/-meth...
متن کاملLocalization of the DAZ gene expression in seminiferous tubules of patients with spermatogenic disorders.
The research on the expression and mutations of DAZ and its homologues in human and other mammals suggests that protein products of these genes can mainly affect development of germinal cells. The aim of the present study was to analyze the expression of the DAZ gene in seminiferous tubules of six men with spermatogenic disorders (hypospermatogenesis and spermatogenic arrest). The results based...
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Background: One of the most growing diseases is the onset of atherosclerosis which can be started from a fetal age. As a result, the intrauterine environment plays a role at risk of spreading this disease. Changes in vascular function considered to be as an indicator for vascular disease. Effective factors on vascular function are enzyme eNOS and apoptotic regulator factors included BCL-2 an...
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Background This study aimed to investigate whether Artificial Seminiferous Tubules (AST) coated with testicular extra cellular matrix (ECM) support maturation of spermatogenic cells from immature testes. MaterialsAndMethods Medical grade tubes coated with testicular ECM were used. Testes from immature mice were loaded in the concentration of 10000- 20000/ml. Tubes were then immersed in germ cel...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2000
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod62.3.748